Tag: substitution practices

Prescriber Attitudes on NTI Drug Substitution: Risks, Regulations, and Current Practices

Prescribers have mixed views on substituting generic versions of Narrow Therapeutic Index drugs. FDA guidelines and state laws influence decisions, with some states requiring patient consent. Real-world data shows higher brand usage for critical NTI drugs like warfarin and tacrolimus. Communication between doctors and pharmacists is key to managing substitution risks. Ongoing research aims to improve safety and trust in generic NTI options.