Author: Nicolas Ghirlando

Post-Surgical Pain Management: Multimodal Strategies to Reduce Opioid Use

Multimodal analgesia reduces opioid use after surgery by combining non-opioid medications like acetaminophen, gabapentin, and NSAIDs. Proven to cut painkiller needs by up to 60%, it’s now the standard of care for most surgeries.

Quality by Design in Generic Drug Development: Modern Science-Based Approaches

Quality by Design (QbD) is now mandatory for generic drug development, shifting focus from end-product testing to science-based design. Learn how QbD improves bioequivalence, cuts approval times, and saves millions-while avoiding common pitfalls.

Canada's Generic Drug System vs. the USA: How Pricing, Supply, and Policy Differ

Canada and the U.S. handle generic drugs in completely different ways. Canada uses centralized pricing to ensure access, while the U.S. relies on competition for lower prices. Here’s how they compare on cost, supply, and patient outcomes.

How to Request Written Medication Instructions You Can Actually Understand

Learn how to ask for clear, easy-to-understand written medication instructions. Know your rights, use proven strategies, and get the information you need to take your meds safely.

Organ Transplant Recipients: Immunosuppressant Drug Interactions and Side Effects

Organ transplant recipients must take lifelong immunosuppressant drugs to prevent rejection, but these medications come with serious side effects and dangerous drug interactions. Learn how tacrolimus, mycophenolate, and steroids affect health - and how to manage risks.

Antibiotics and Myasthenia Gravis: What You Need to Know About Neuromuscular Weakness Risks

Antibiotics can worsen myasthenia gravis symptoms by interfering with nerve-muscle signals. Learn which antibiotics are safest, which to avoid, and how to manage infection risks without triggering a crisis.

Contamination Issues in Generic Drugs: Recent Cases and How to Prevent Them

Recent contamination cases in generic drugs-including NDMA in blood pressure meds and benzene in Mucinex-reveal serious safety gaps. Learn which drugs are at risk, where they come from, and how to protect yourself.

How to Reduce Pill Burden with Combination Medications for Seniors

Combination medications can cut pill burden for seniors by merging multiple drugs into one pill, improving adherence, lowering costs, and reducing health risks. Learn how they work, who benefits most, and how to talk to your doctor about switching.

Intermittent Fasting for Weight Loss: What Time-Restricted Eating Really Does

Time-restricted eating, a form of intermittent fasting, helps with weight loss by aligning meals with your body's natural rhythm. Studies show it leads to 1.7-2.5 kg more weight loss than unrestricted eating, without strict calorie counting.

DOACs in Renal Impairment: How to Adjust Doses to Prevent Bleeding and Clots

DOACs are effective blood thinners but require precise dosing in kidney disease. Learn how to adjust apixaban and avoid dangerous mistakes with rivaroxaban, dabigatran, and edoxaban using Cockcroft-Gault calculations.